In a recent study, researchers found that high amounts of dietary sugar in the typical Western diet might increase the risk of breast cancer and metastasis to the lungs. They demonstrated the dietary sugar's effect on an enzymatic signaling pathway known as 12-LOX (12-lipoxygenase) and found that sucrose intake in mice comparable to levels of Western diets led to increased tumor growth and metastasis, when compared to a non-sugar starch diet.